Dr. Gladman is professor of medicine at the University of Toronto, and senior scientist at the Toronto Western Research Institute. She is deputy director of the Centre for Prognosis Studies in the Rheumatic Diseases, director of the Psoriatic Arthritis Program, University Health Network, and co-director of the University of Toronto Lupus Clinic.
Dr. Gladman has researched both systemic lupus erythematosus and psoriatic arthritis with emphasis on database development, prognosis studies, genetic markers for disease susceptibility and expression, assessment instruments and quality-of-life measures. She has also been involved in clinical trials in these conditions.
Dr. Gladman has 620 peer-reviewed publications, 132 chapters and invited publications, and more than 860 published abstracts.
Important contributions to psoriatic arthritis include the recognition that the disease was more severe than previously noted. Dr. Gladman and colleagues demonstrated that psoriatic arthritis progressed over time, and was associated with increased mortality. Moreover, her group identified predictors for disease progression and mortality. On the other hand, they also identified patients who achieved remission.
Dr. Gladman is past-president of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), an international group of rheumatologists and dermatologists whose objectives are to study psoriasis and psoriatic arthritis. She is also a member of the executive of the Spondyloarthritis Research Consortium Canada (SPARCC).
She was the recipient of the Verna Wright Prize for outstanding contribution to the field of psoriatic arthritis presented by the International Psoriatic Arthritis Group in Naples Italy. She is a founding member and past-chairperson the Systemic Lupus International Collaborating Clinics Group and is a Master of the American College of Rheumatology. Her work has been supported by research grants from the Arthritis Society, the Canadian Institutes of Health Research and the Krembil Foundation.